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Latest From Conexiant

FDA: Montelukast May Impact Brain Functioning

Laboratory analysis reveals montelukast demonstrates “significant binding” to multiple brain receptors, suggesting more extensive neurological activity than previously understood.

Allergy & Immunology December 4th 2024

Tags: ADVERSE EVENTS ASTHMA DRUG SAFETY & INTERACTIONS FDA MENTAL HEALTH

New UTI Guidelines Reveal Major Evidence Gaps

Of 37 clinical questions examined by international experts, only 6 received clear evidence-based recommendations, highlighting significant gaps in UTI management evidence.

Family Medicine/General Practice November 27th 2024

Tags: ANTIBIOTICS EVIDENCE-BASED MEDICINE GUIDELINES/RECOMMENDATIONS URINARY HEALTH

Updated Guidance on Contraceptive Use

The 2024 U.S. SPR emphasizes the paramount importance of personal autonomy in contraceptive decision-making, particularly in light of historical and ongoing contraceptive coercion and reproductive mistreatment in the United States.

Family Medicine/General Practice August 20th 2024

Tags: CONTRACEPTION/BIRTH CONTROL GUIDELINES/RECOMMENDATIONS REPRODUCTIVE & SEXUAL HEALTH WOMEN'S HEALTH

Transgender Women Benefit from Prostate Cancer Screenings

This groundbreaking study provides new insights into the risk of prostate cancer in transgender women, emphasizing the need for tailored screening and awareness among healthcare providers.

Oncology, Medical September 11th 2023

Tags: CANCER SCREENING CLINICAL RESEARCH IMAGING/SCREENING LGBTQIA+ MEDICINE PROSTATE CANCER

Using Radiation to Treat Cancer

The Evolution of Radiation Therapy Explore the evolution of radiation therapy with Dr. Heath Skinner and understand the advancements in 3DCRT, IMRT/VMAT, proton therapy, stereotactic radiation, and brachytherapy. Dr. Heath D. Skinner, esteemed chair and medical director of the Department of Radiation Oncology at UPMC Hillman Cancer Center, delves into the dynamic and transformative world of radiation oncology in this enlightening Continuing Medical Education (CME) activity. A noted specialist in the treatment of head, neck, and lung cancer, Dr. Skinner’s commitment to advancing clinical research underscores his discussions, which aim to educate and inform on the significant advancements in radiation therapy over recent decades. The CME activity is designed as a comprehensive examination of the evolution of radiation therapy. Dr. Skinner outlines a clear trajectory of progress, highlighting the development from conventional three-dimensional conformal radiation therapy (3DCRT) to more sophisticated techniques such as intensity-modulated radiation therapy/volumetric-modulated arc therapy (IMRT/VMAT), and further to the precision of proton therapy. These techniques, each with unique advantages, have shaped modern oncology practices and offer promising improvements in patient outcomes. Further delving into the field, Dr. Skinner also elucidates the intricacies of stereotactic radiation and brachytherapy as additional pillars in the modern cancer treatment paradigm. […]

Oncology, Medical May 22nd 2023

Tags: CANCER CARE CME RADIOTHERAPY

Johns Hopkins Hepatologists Detect Liver Cancer in Urine Test

Johns Hopkins researchers develop breakthrough urine test for liver cancer, increasing early detection rates by supplementing traditional AFP testing. A groundbreaking screening test for hepatocellular carcinoma (HCC), developed by Amy Kim, a hepatologist at Johns Hopkins, and her team, has demonstrated the potential to detect liver cancer at an earlier stage than the current standard-of-care. This novel diagnostic approach seeks to identify a subset of genetic biomarkers in urine associated with HCC, thereby supplementing the traditional combination of ultrasound and alpha-fetoprotein (AFP) blood testing. AFP tests have shown variable effectiveness with detection rates ranging between 40% and 90%, and a substantial number of liver cancer patients exhibit low AFP levels or misleadingly high levels due to liver disease, reducing the reliability of AFP as a singular biomarker. The study, conducted in collaboration with the Baruch S. Blumberg Institute and published in the British Journal of Cancer in 2022, analyzed samples from over 600 patients at high risk for liver disease across five medical centers. Kim’s team demonstrated that the combined use of urine circulating tumor DNA (ctDNA) testing and AFP increased detection sensitivity from 40% to 77% in early-stage liver cancer, and from 62% to 92% in the very early […]

Hepatology May 22nd 2023

Tags: IMAGING/SCREENING LIVER CANCER MEDICAL BREAKTHROUGHS

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