Articles related to PREGNANCY COMPLICATIONS

Semaglutide use before or during pregnancy was associated with greater gestational weight gain and several adverse outcomes in a retrospective cohort, although similar findings among former users complicate attribution to direct fetal exposure.

An expert presentation at an obstetric ultrasound congress highlighted how real-time ultrasound guidance may improve the completeness and safety of early pregnancy procedures by maintaining instrument visualization and reducing procedural complications.

Fetal macrosomia showed the strongest association with shoulder dystocia in a single-center case-control study of vaginal deliveries. Maternal overweight and diabetes also contributed to risk, while the low event count and retrospective design limit prediction.

Hospitals in multiple states have adopted postpartum notification wristbands intended to improve recognition of post-delivery complications. While proponents cite increased awareness and lower readmission rates at some institutions, evidence supporting broad outcome benefits remains limited.

Maternal anti-HPA-1a antibodies inhibited β3 integrin activation in laboratory models, with stronger functional inhibition in severe FNAIT cases. The findings suggest a mechanism beyond platelet clearance, but clinical validation remains necessary.

A case report identified high-titer anti-RhD IgG antibodies in maternal breast milk as a potential source of ongoing hemolysis in an infant with persistent HDFN after exchange transfusion. The finding highlights a possible mechanism for delayed disease persistence but requires further validation.