Articles related to MATERNAL-FETAL MEDICINE

Semaglutide use before or during pregnancy was associated with greater gestational weight gain and several adverse outcomes in a retrospective cohort, although similar findings among former users complicate attribution to direct fetal exposure.

An expert presentation at an obstetric ultrasound congress highlighted how real-time ultrasound guidance may improve the completeness and safety of early pregnancy procedures by maintaining instrument visualization and reducing procedural complications.

Fetal macrosomia showed the strongest association with shoulder dystocia in a single-center case-control study of vaginal deliveries. Maternal overweight and diabetes also contributed to risk, while the low event count and retrospective design limit prediction.

New consensus guidance favors once-daily oral iron and simplified IV administration, including fewer test doses, premedications, and infusion visits. Several recommendations depart from established protocols and require formulation-specific clinical judgment.

Maternal anti-HPA-1a antibodies inhibited β3 integrin activation in laboratory models, with stronger functional inhibition in severe FNAIT cases. The findings suggest a mechanism beyond platelet clearance, but clinical validation remains necessary.

Experts highlighted ongoing barriers and knowledge gaps affecting reproductive care for transgender and gender-diverse patients while outlining strategies to support pregnancy, postpartum care, and fertility discussions in affirming clinical environments.