Articles related to MATERNAL-FETAL MEDICINE

ACOG has revised its approach to postmenopausal bleeding evaluation, recommending combined transvaginal ultrasonography and endometrial sampling for most patients at initial presentation. The update reflects rising endometrial cancer incidence, evolving evidence on cancer subtypes, and recognized limitations of ultrasound-only evaluation.

Female mice recovering from a single ketamine exposure demonstrated microglia-driven neuroplasticity through FKBP51 activation, while male mice did not. The findings identify a sex-specific biologic pathway in a preclinical model, and human relevance remains unconfirmed.

Pregnancy is well tolerated for many women with congenital heart disease, but outcomes vary substantially by underlying lesion and clinical characteristics. Current guidance emphasizes multidisciplinary counseling, structured risk assessment, and individualized management before conception.

A federal court allowed a lawsuit against a hospital to proceed after a patient’s placenta was destroyed despite a signed release form. The ruling focused on contractual obligations and patient-directed handling of biological specimens.

Prenatal fish oil supplementation was associated with small differences in cerebral blood flow and oxygen metabolism at age 10. Cognitive and psychopathology outcomes showed no significant association.

FcγRIII-mediated macrophage phagocytosis emerges as the dominant mechanism of platelet destruction in FNAIT, suggesting targeted receptor blockade could offer a future therapeutic approach, though evidence remains preclinical.