Articles related to Psychiatric/Mental Health Nursing

In a phase 3 trial of 214 adults with generalized anxiety disorder, a single dose of DT120 orally disintegrating tablets produced greater reductions in anxiety scores than placebo through 12 weeks. Full peer-reviewed data and longer-term results remain pending.

A rapid review found that ADHD stimulant misuse declined in several recent US surveys, particularly among younger adults, although millions continued to report misuse. Evidence linked frequent misuse with polysubstance use, while long-term health consequences remain poorly characterized.

Individuals with psychiatric disorders demonstrated reduced flexibility in brain network reconfiguration across cognitive states in a transdiagnostic neuroimaging study. The findings linked dynamic brain patterns with symptom profiles but did not establish causality or clinical applicability.

Adjunctive active VNS was associated with greater suicidal ideation improvement than sham stimulation in patients with markedly treatment-resistant depression. The exploratory analysis was not powered as a confirmatory suicide-outcomes trial.

An observational study associated repeated gabapentin prescribing with higher rates of dementia and mild cognitive impairment, particularly among adults aged 18 to 64 years. Experts emphasized that the findings do not establish causality and should be interpreted cautiously.

A Phase 2 trial of luvesilocin reported rapid reductions in postpartum depression symptoms, with most treated participants reaching remission within seven days. The investigational psychedelic has received FDA Breakthrough Therapy designation, but Phase 3 confirmation remains pending.