Articles related to COMORBIDITIES

Older adults with advanced or metastatic urothelial carcinoma treated with enfortumab vedotin experienced substantially higher rates of severe toxicity and treatment discontinuation than younger patients, while survival outcomes appeared similar across age groups.

Women with bulimia nervosa demonstrated smaller total cortical surface area and reduced nucleus accumbens volume compared with healthy controls in a large international neuroimaging study, with more frequent binge-eating episodes associated with additional structural differences across brain regions involved in reward, cognitive control, and interoception.

Youth with ADHD and comorbid ASD showed distinct medication patterns and greater psychiatric burden in a large EHR cohort. The observational findings did not establish causal treatment effects.

Most newly diagnosed focal epilepsy patients required more than a year and more than one antiseizure medication to reach seizure freedom in a multicenter cohort.

Bariatric surgery volumes peaked in 2022 and have fallen since, with sleeve gastrectomy losing ground and Roux-en-Y conversions climbing as GLP-1 prescriptions expand.

“A fully oral, inexpensive NMDA-AMPA modulation strategy may offer a practical alternative for patients with the bipolar obsessive-compulsive disorder phenotype who respond poorly to conventional approaches.” — Ngo Cheung, MBBS