Articles related to EPILEPSY/SEIZURES

Late-breaking sessions at AAN 2026 spanned rare disease, migraine prevention, epilepsy, FTD, MS, early Alzheimer’s, neuropathic pain, and stiff person syndrome, with mixed signals across disease-modifying and symptomatic therapies.

The American Epilepsy Society released the first dedicated treatment guideline for infantile epilepsy. Two strong surgical recommendations sit alongside conditional pharmacological and dietary guidance.

The study objectives were to compare the outcomes of 6-year-old children of women with epilepsy (WWE) vs those of healthy pregnant women (HW), and to assess the association of outcomes to third-trimester antiseizure medications (ASM) exposures.

Although most of these patients had no response to multiple seizure medications, the 9 who were treated with vitamin B6 supplementation had resolution of their seizures.

After adjustment for demographic and clinical factors, cenobamate was associated with statistically significant higher odds of achieving a 50% or greater reduction in seizure frequency at 6 months vs all three comparators.

The NSGC CPC strongly recommends that all individuals with unexplained epilepsy be offered genetic testing, regardless of age.