Articles related to MIGRAINES/HEADACHES

Multimodal MRI analysis identified two distinct migraine subgroups in a 111-patient cohort, with one cluster showing widespread cortical-subcortical connectivity changes and lower cortical volumes tied to greater disease burden and disability.

A systematic review of 43 randomized controlled trials found high-certainty evidence that multiple CGRP-targeted therapies reduced monthly migraine headache days by approximately 2 days versus placebo in adults with chronic migraine.

The American College of Physicians Performance Measurement Committee reviewed the single MIPS quality measure tied to migraine and declined to support it, citing outdated guideline basis, missing exclusions, and lack of physician-level testing.

Late-breaking sessions at AAN 2026 spanned rare disease, migraine prevention, epilepsy, FTD, MS, early Alzheimer’s, neuropathic pain, and stiff person syndrome, with mixed signals across disease-modifying and symptomatic therapies.

Stroke incidence is rising in women under 45, with attention turning to non-traditional risk factors including handheld percussive devices, sexual strangulation, migraine with aura, peripartum vascular changes, and early menopause.

Based on the researchers’ series, patients who develop VS after an inciting event or related to an underlying comorbidity may have a better prognosis than those in whom it develops spontaneously.