Articles related to NEUROLOGICAL DISORDERS

Singer-songwriter Carly Simon described years of mobility limitations initially attributed to arthritis and joint replacement recovery before receiving a Parkinson’s disease diagnosis. Her experience highlights the diagnostic challenges created when evolving symptoms appear consistent with existing conditions.

Multimodal MRI analysis identified two distinct migraine subgroups in a 111-patient cohort, with one cluster showing widespread cortical-subcortical connectivity changes and lower cortical volumes tied to greater disease burden and disability.

Peripapillary hyperreflective ovoid mass-like structures showed no significant correlation with intracranial pressure levels in a cross-sectional cohort of 54 patients with idiopathic intracranial hypertension, suggesting anatomic rather than pressure-driven origins.

A middle-aged woman with a four-year bipolar disorder diagnosis continued deteriorating despite psychiatric treatment until clinical reassessment pointed toward anti-NMDA receptor encephalitis, an autoimmune condition whose psychiatric prodrome frequently delays correct diagnosis.

Benjamin Tolchin, MD and lead authors of the study remarked: “Most people with functional seizures do not receive targeted and evidence-based treatment, contributing to ongoing functional seizures and disability.”

“We always have to remember that these types of tragedies are never just one thing or one factor… the most important thing is that a lot of these symptoms, if caught and detected early, they can be helped.” — Michael Alosco, PhD