Articles related to NEUROLOGICAL DISORDERS

A single, unifying etiology for FMD is not yet known, and this article from Practical Neurology characterizes diagnosing the disorder as “a process involving a careful history and examination for positive signs to rule in the diagnosis, while considering the differential diagnoses of functional presentations.”

To date, no Cdk5 inhibitor has been approved to treat any neuropsychiatric or degenerative diseases due to challenges at the blood-brain barrier. James Bibb, Ph.D., and colleagues seek to change that notion with their brain-permeable compound, 25-106.

A fact-filled video program all about ALZ-801 (valiltramiprosate), an oral medication with a novel mode of action that aims to slow or stop Alzheimer’s disease altogether.

Hear, watch, or read the top-line observations from a Harris Poll that included more than 360 patients and 120 caregivers on the impact of symptomatic neurogenic orthostatic hypotension (nOH). Suffice, many described severe limitations to their ability to perform activities that are necessary for day-to-day living.

Data for this study came from Danish medical registries over a 20-year period for 247,305 people who visited a hospital or were prescribed antiviral medication for herpes zoster and 1,235,890 people who did not have the disease. These individuals were an average age 64. Up to 21 years later, 9.7% of those with vs. 10.3% of those without herpes zoster developed dementia.

MRI data were evaluated on 92 active professional mixed martial arts fighters to understand the effects of sparring on white matter and regional brain volumes. The researchers found a “very strong significant association between the amount of sparring per week and white matter hyperintensity volume and bilateral caudate size.” According to one of the authors of the study, Aaron I. Esagoff, BS, a medical student at Johns Hopkins University School of Medicine and intern with the FDA: “The white matter hyperintensities might indicate some damage that comes with sparring. But the larger bilateral caudate compared to individuals who spar less might indicate a protective effect.”