Articles related to CORRELATIONS/LINKS

In a propensity-matched analysis of more than 66,000 adults with hypertension, blood-brain barrier (BBB)-crossing antihypertensives were associated with a 16% lower dementia risk than BBB-non-crossing agents. The observational design prevents causal conclusions but adds to growing interest in whether some antihypertensives may influence cognitive outcomes beyond blood pressure control.

A 10-year retrospective cohort study associated glaucoma with higher risks of Alzheimer disease, vascular dementia, and other neurodegenerative diagnoses, although administrative coding and surveillance bias limit causal interpretation.

Daily consumption of sugar-sweetened beverages was associated with more than double the risk of gastric cancer in two large U.S. prospective cohorts, although the findings did not establish causality and require confirmation in additional studies.

Double-filtration plasmapheresis reduced circulating concentrations of several PFAS in small patient samples, while microplastic changes varied by polymer. The exploratory findings do not support apheresis for environmental pollutant removal.

A multicenter cross-sectional study associated symptomatic uncomplicated diverticular disease with reduced microbial diversity and distinct taxonomic and predicted functional patterns. The findings remain hypothesis-generating and require validation in larger, longitudinal cohorts.

Use of estrogen-only hormone therapy in women over age 70 was associated with lower rates of dementia diagnoses and reduced Alzheimer-related pathology across large observational cohorts. The findings identify an association but do not establish a preventive effect against dementia.