Articles related to Internal Medicine

A mechanistic compartmental model integrating menstrual fluid binding data estimated that less than 0.3% of theoretically released lead from tampons would be available for vaginal tissue absorption under a four-hour wear scenario.

Lerochol (lerodalcibep-liga), a once-monthly self-administered PCSK9 inhibitor, is now commercially available as adjunctive LDL-C-lowering therapy for adults with hypercholesterolemia, including heterozygous familial hypercholesterolemia.

A single-institution case series of 13 biopsy-proven hydroxychloroquine cardiomyopathy patients documented variable outcomes after drug cessation, ranging from full functional recovery to progression requiring advanced heart failure therapies.

A Swedish national cohort analysis linked bereavement to elevated incident cardiovascular disease risk before and during the COVID-19 pandemic, with the strongest pandemic-period association following partner loss.

The American College of Physicians Performance Measurement Committee reviewed the single MIPS quality measure tied to migraine and declined to support it, citing outdated guideline basis, missing exclusions, and lack of physician-level testing.

Blarcamesine (Anavex 2-73), an investigational once-daily oral autophagy enhancer, showed sustained cognitive, functional, and brain volume benefits through nearly 3 years in a Phase 2b/3 trial and open-label extension presented at AD/PD 2026.