Articles related to Internal Medicine

A review identified 15 reports of Wernicke encephalopathy among patients receiving GLP-1 therapies, most accompanied by poor intake, vomiting, weight loss, or malnutrition, highlighting a rare safety signal without establishing drug-related causality.

In an adaptive randomized trial of adults with long COVID, fluvoxamine modestly reduced fatigue and improved quality-of-life scores through 90 days, while metformin findings remained inconclusive after dose modification and early termination.

Extensively drug-resistant Shigella has increased in US surveillance, with sexual transmission emerging as an important route among some populations. Rising multidrug resistance may complicate treatment, although many infections remain self-limited.

ACP places estrogen-based therapy first in its pharmacologic pathway for menopausal vasomotor symptoms, with nonhormonal alternatives for contraindications or intolerance. Recommendation strength and evidence certainty vary, and long-term safety evidence remains limited.

The American Heart Association has updated infective endocarditis guidance to incorporate the 2023 Duke/ISCVID diagnostic criteria, advanced microbiologic diagnostics, contemporary imaging recommendations, and evolving antimicrobial treatment approaches while emphasizing multidisciplinary management.

In a prospective cohort of more than 112,000 French adults, higher intake of several commonly used food preservatives was associated with increased risks of hypertension and cardiovascular disease, though the observational design cannot determine whether the additives themselves caused the observed outcomes.