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Neurology Advisor
A network meta-analysis of 15 randomized trials found that no pharmacologic treatment outperformed placebo for MS-related fatigue severity, though amantadine and fampridine showed statistically significant and potentially clinically meaningful improvements in fatigue-related daily functioning.
Internal Medicine June 23rd 2026
Annals of Internal Medicine
“Fluvoxamine may have a beneficial role in the clinical management of fatigue in long COVID, although the condition encompasses a broad range of clinical manifestations beyond fatigue alone.” — REVIVE Trial, Annals of Internal Medicine
Hospital Medicine April 10th 2026
GoodRx for Healthcare Professionals
Up to 45% of people in the US experience fatigue, making medication-induced drowsiness a significant clinical consideration when prescribing commonly used drug classes.
Clinical Pharmacology April 29th 2025
MDLinx
Fatigue from hospital shift work can have physical health consequences similar to those of intoxication, impacting a worker’s safety and alertness, especially when driving.
All Specialties June 18th 2024
Several medications, including antihistamines, muscle relaxers, and benzodiazepines, are known to cause fatigue. Understanding these effects and managing patient expectations can help mitigate this common side effect.
All Specialties June 4th 2024
Healthgrades for Professionals
Persistent fatigue is more than just feeling tired; it can be a symptom of various underlying medical conditions. Understanding the potential causes is crucial for effective patient diagnosis and treatment.
Allergy & Immunology September 7th 2023