Articles related to PEDIATRIC NEUROLOGY

A phase 3 randomized trial of 449 children with intracranial ependymoma found no significant event-free or overall survival benefit from adding maintenance chemotherapy after radiation, while molecular markers — particularly 1q gain and 6q loss — identified a high-risk posterior fossa subgroup with substantially worse outcomes.

The American Epilepsy Society released the first dedicated treatment guideline for infantile epilepsy. Two strong surgical recommendations sit alongside conditional pharmacological and dietary guidance.

The NSGC CPC strongly recommends that all individuals with unexplained epilepsy be offered genetic testing, regardless of age.

Progress in perinatal care has improved survival for children born very preterm (VPT), but these children remain at higher risk of cognitive impairment compared with children born at term.

Given the widespread use of this medication, even a small increase in risk could have major public health implications.

“These autism sensory differences—from altered habituation patterns in utero to atypical newborn responses—offer clinicians measurable indicators that precede behavioral presentations.”