Articles related to GASTRO/HEP DISORDERS

Timely diagnosis and intervention are crucial in managing acute abdominal pain, as emergency general surgery is an independent risk factor for postoperative complications and death.

Schistosomiasis should be considered in the differential diagnosis for patients presenting with rectal bleeding, particularly those with a history of freshwater exposure in endemic areas.

Dupilumab significantly induced histologic remission in 68% of children with eosinophilic esophagitis compared to 3% in the placebo group, according to a phase 3 trial.

Pantoprazole demonstrated a significant reduction in upper gastrointestinal bleeding in mechanically ventilated ICU patients, offering a viable prophylactic option without impacting overall mortality rates.

A phase 2 trial found that tirzepatide, administered once weekly, significantly improved the resolution of MASH and fibrosis stages in patients with moderate to severe liver fibrosis. These results highlight tirzepatide’s potential as a treatment option, emphasizing the need for further research to validate these findings in larger, long-term studies.

Early oral or enteral feeding in acute pancreatitis patients is now recommended to minimize complications and improve recovery, moving away from traditional NPO and parenteral nutrition practices.