Articles related to GASTRO/HEP DISORDERS

A case report describes duodenal ulcer perforation in a woman receiving tirzepatide for weight loss, occurring shortly after dose escalation, though important confounders prevent conclusions about a causal drug relationship.

Updated joint ESPGHAN/NASPGHAN guidelines for pediatric Helicobacter pylori infection emphasize antimicrobial stewardship, susceptibility-guided therapy, and more selective testing strategies. The recommendations also introduce several changes regarding screening, incidental findings, and management of associated conditions.

A meta-analysis of 14 observational studies found that very high chili pepper consumption was associated with increased gastrointestinal cancer risk, particularly esophageal cancer. The findings were observational and did not establish a causal relationship between chili pepper intake and cancer development.

More than 4,100 laboratory-confirmed cyclospora infections have been reported across 41 states during a larger-than-usual US outbreak. Investigators continue to search for the source, and no food product has been definitively confirmed as responsible.

A multi-fiber formulation improved bowel frequency and stool consistency in adults with functional constipation in a short-term study evaluating combined fiber mechanisms.

A quiz-format clinical vignette from Consultant360 walked through imaging selection and analgesia decisions in a 47-year-old woman presenting with acute right upper quadrant pain, using the case to reinforce diagnostic sequencing in the acute abdomen.