Articles related to LIVER DISEASE

A multicenter analysis of adults with biopsy-confirmed MASLD found that roughly one-quarter of cirrhosis cases developed before age 50, with type 2 diabetes and genetic susceptibility associated with earlier progression.

A 25-year-old man with approximately three years of daily high-volume energy drink consumption developed mixed-pattern liver injury with cholestatic histology. Exposure cessation coincided with substantial biochemical improvement, although causality remained uncertain and alternative explanations were not fully excluded.

Among pediatric gastroenterologists, there is agreement that ALT ≥ 22 U/L for boys and ALT ≥ 22 U/L for girls should be the cutoffs when to determine the ALT levels are increased.

“Mean LOS post-transplant was significantly shorter in the post-APP cohort (P = .005). The mean LOS for the pre- and post-APP cohorts were 22.4 and 16.5 days, respectively.”

Preemptive TIPS has been shown to improve overall mortality in patients with variceal hemorrhage… the 1-year probability of remaining free of failure to control bleeding was 97% in the preemptive TIPS group vs 50% in standard-of-care group.

In patients with both cirrhosis and atrial fibrillation, apixaban initiation was associated with lower rates of major bleeding compared to rivaroxaban or warfarin, without compromising thromboembolic protection.