Articles related to POSTMENOPAUSAL CARE

Small observational studies linked menopausal hormone therapy with improvements in cognitive and mood symptoms, while a large meta-analysis found no overall dementia association, leaving cognitive treatment benefits insufficiently established.

Analysis of postmenopausal ovarian tissue from 28 women found that ovaries continue to undergo molecular remodeling decades after menopause, with age-related increases in inflammatory and tissue-remodeling pathways that overlap with biologic processes observed in ovarian cancer.

A large Danish registry study found that current use of oral menopausal hormone therapy was associated with increased venous thromboembolism risk, while transdermal therapy was not generally associated with higher thrombotic rates across regimens, doses, or durations.

Testosterone prescribing for women has risen sharply despite the absence of FDA-approved female-specific products. The increase is occurring alongside pharmacy dispensing barriers and renewed regulatory attention, while guideline-supported use remains largely limited to hypoactive sexual desire disorder in postmenopausal women.

“In this observational study, women who used menopausal hormone therapy lost about 35% more weight than women taking tirzepatide alone. Because this was not a randomized trial, we cannot say hormone therapy caused additional weight loss,” says Maria Daniela Hurtado Andrade, M.D., Ph.D., endocrinologist at Mayo Clinic and senior author of the study.

Collagen, once relegated to cosmetic marketing, now shows potential as a legitimate adjunct in the prevention or management of age-related decline in connective tissue integrity.