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A multi-fiber formulation improved bowel frequency and stool consistency in adults with functional constipation in a short-term study evaluating combined fiber mechanisms.

A network meta-analysis of 15 randomized trials found that no pharmacologic treatment outperformed placebo for MS-related fatigue severity, though amantadine and fampridine showed statistically significant and potentially clinically meaningful improvements in fatigue-related daily functioning.

Opioid prescribing for cancer patients reporting no pain declined substantially across a single Connecticut health system from 2016 to 2020, while prescribing for patients reporting pain remained stable.

A Cureus case report describes complete fecaloma resolution after two 1 L Classic Coca-Cola enemas in an 82-year-old woman with dementia whose impaction failed conservative management.

Smartwatch-derived nighttime scratching metrics correlated moderately with disease severity and short-term treatment response in a small pediatric atopic dermatitis cohort.

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