Articles related to STATINS
Low-Dose Statin Bests Six Commonly Used Cholesterol Health Supplements
The statin group experienced an average LDL-C reduction of 37.9%, according to the results of the single-center, prospective, randomized, single-blind SPORT study (Supplements, Placebo, or Rosuvastatin), while those who took dietary supplements experienced LDL-C changes similar to those in the placebo group. Additionally, rosuvastatin-treated patients experienced average decreases in triglycerides of 19% and total cholesterol of 24%. For any of the supplements, there were no differences in either total cholesterol or triglycerides when compared to placebo.
Cardiology November 14th 2022
Guidance Developed for Addressing Use of Nonstatin Therapies
These recommendations “attempt to provide practical guidance for clinicians and patients regarding the use of nonstatin therapies to further reduce ASCVD risk in situations not covered by the guideline until such time as the scientific evidence base expands.”
Cardiology September 8th 2022
Statin Use for the Primary Prevention of Cardiovascular Disease (CVD) in Adults: US Preventive Services Task Force (USPSTF) Recommendation Statement
The USPSTF comes to the conclusion that statin use has at least a moderate net benefit for adults aged 40 to 75 who have no prior history of CVD, at least one CVD risk factor, and an estimated 10-year CVD event risk of 10% or greater. There is at least a marginal net benefit from using statins to prevent CVD events and all-cause mortality in adults aged 40 to 75 who have no prior history of CVD, at least one of these risk factors, and an estimated 10-year CVD event risk of 7.5% to less than 10%. Still, is the evidence enough?
Cardiology September 6th 2022
The “Anti-Statin” Movement: Untangling the Web of Misinformation
A conversation with Ann Marie Navar, MD, PhD, associate professor of cardiology at UT Southwestern in Dallas, Texas and associate editor of JAMA Cardiology, who discusses common statin-related myths, the safety of statin therapy, and reliable sources of information for patients.
Cardiology July 19th 2022
Physicians Debate Statin Use for Patients with Cardiovascular Disease
In a look “Beyond the Guidelines,” a preventive cardiologist and a general internist discuss their approach in the case of a 57-year-old woman with high cholesterol and a family history of heart disease.
Cardiology June 23rd 2022
Meta-Analysis Questions Strength of Ties Between Statin-Induced LDL Lowering, CV Outcomes
A meta-analysis published in JAMA Internal Medicine has concluded that the link between statin-induced LDL lowering and reduction of CV outcomes may not be as robust as previously assumed. According to the researchers, the absolute risk reduction associated with statin use for all-cause mortality was 0.8% (95% CI, 0.4-1.2), whereas for MI it was 1.3% (95% CI, 0.9-1.7) and for stroke it was 0.4% (95% CI, 0.2-0.6). Absolute risk reduction figures were slightly higher for secondary prevention than for primary prevention.
Cardiology March 22nd 2022