Articles related to LIPID HEALTH

In a phase 2b trial, plozasiran significantly reduced fasting triglyceride levels at 24 weeks in patients with mixed hyperlipidemia, with the 50 mg quarterly dose achieving a mean reduction of 62.4 percentage points. This study highlights the potential of APOC3 inhibition as a therapeutic strategy for lipid management.

Statins, although effective at lowering cholesterol, may inadvertently impair immune function by reducing vitamin D synthesis. This opinion piece examines how this could have influenced COVID-19 outcomes, highlighting critical considerations for clinical practice.

Recent studies show that specific exercise regimens can reduce harmful lipid levels and improve muscle and skin health, offering new strategies to counteract aging.

The recent trial assessing CSL112’s role in enhancing cholesterol efflux capacity showed no significant reduction in cardiovascular events over one year among patients post-acute myocardial infarction, maintaining a safety profile consistent with placebo.

This recent research highlights the potential impact of lipid accumulation on Alzheimer’s disease, focusing on the differential role of APOE gene variants in lipid transport within the brain, a crucial aspect that may shape future therapeutic directions.

Physicians should be aware of the evolving research regarding statins and dementia. Recent studies provide mixed evidence, with some suggesting a potential protective effect of statins against dementia, underscoring the necessity for individualized patient assessments.