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SAGE Open Medical Case Reports (SCO)
Three adults receiving semaglutide or tirzepatide preserved or increased lean soft tissue while losing weight alongside resistance training and protein-focused diets, although the uncontrolled case series cannot determine which strategies produced these outcomes.
Endocrinology, Diabetes, Metabolism October 1st 2026
News Medical
Reductions in lean body mass are likely concentrated in non-contractile components rather than reflecting a clear decline in muscle function.
Endocrinology, Diabetes, Metabolism March 27th 2026
Practical Neurology
Muscle cramps are common in the general population, with reported prevalences ranging from 37% to 95%. When frequent or severe, muscle cramps can cause prolonged postcramp soreness and can diminish quality of life by disrupting sleep, limiting physical activity, and provoking anxiety about symptom recurrence.
Emergency Medicine August 20th 2025
Health
Muscle protein synthesis requires strategic amino acid delivery, with leucine serving as the primary trigger for anabolic processes across all age groups.
Endocrinology, Diabetes, Metabolism June 26th 2025
GoodRx for Healthcare Professionals
Joint and muscle pain are established side effects across multiple medication classes including antibiotics, cholesterol-lowering agents, and cancer therapies, with varying onset timing, risk factors, and management approaches that clinicians should recognize to optimize treatment adherence.
Cardiology May 6th 2025
It’s not clear what causes leg cramps. But researchers believe some things can trigger cramps, such as: dehydration, electrolyte imbalances, muscle fatigue.
Endocrinology, Diabetes, Metabolism April 2nd 2025