Articles related to Gastroenterology

Mayim Bialik reports prolonged gastrointestinal symptoms after one dose of an unnamed GLP-1 medication taken for autoimmune symptoms. Her account describes individual intolerance, not the frequency of severe reactions or evidence of autoimmune benefit.

A case report describes duodenal ulcer perforation in a woman receiving tirzepatide for weight loss, occurring shortly after dose escalation, though important confounders prevent conclusions about a causal drug relationship.

A multicenter analysis of adults with biopsy-confirmed MASLD found that roughly one-quarter of cirrhosis cases developed before age 50, with type 2 diabetes and genetic susceptibility associated with earlier progression.

Among nearly 1 million UK adults, preference for very hot beverages and consumption of at least six hot drinks daily were associated with higher esophageal squamous cell carcinoma risk, but not materially with adenocarcinoma.

Updated joint ESPGHAN/NASPGHAN guidelines for pediatric Helicobacter pylori infection emphasize antimicrobial stewardship, susceptibility-guided therapy, and more selective testing strategies. The recommendations also introduce several changes regarding screening, incidental findings, and management of associated conditions.

New consensus guidance favors once-daily oral iron and simplified IV administration, including fewer test doses, premedications, and infusion visits. Several recommendations depart from established protocols and require formulation-specific clinical judgment.