Articles related to SURGICAL ONCOLOGY

Vitreoretinal surgeons describe off-label fibrin glue application as a localized tamponade alternative for rhegmatogenous retinal detachment repair, hemorrhage control, and retinal edge stabilization in cases where gas or silicone oil poses prohibitive patient or logistical constraints.

Perioperative apalutamide plus ADT, six months before and after radical prostatectomy, achieved a ninefold improvement in major pathologic response and a 20% reduction in metastasis-free survival events versus placebo plus ADT in patients with high-risk localized or locally advanced prostate cancer in a phase 3 trial.

Neoadjuvant apalutamide plus abiraterone and ADT before radical prostatectomy was associated with improved 12-month potency recovery and lower positive surgical margin rates compared with surgery alone in a small phase 2 trial of men with high-risk localized prostate cancer.

The ABCDE warning signs help spot melanoma early, so counsel your patients regarding Asymmetry, Border, Color, Diameter, and Evolving (the mole or spot changes in size, shape, or color. It may also start to bleed, itch, or crust).

“Patients treated in the Optune Pax arm had a median time to pain progression of 15.2 months compared to 9.1 months.” — PANOVA-3 Trial, FDA Approval Announcement

Statistical models incorporating individual clinical and tumor characteristics showed superior accuracy when validated against standardized clinical trial data compared to retrospective prediction tools.