Articles related to SKIN CANCER

TNF-alpha inhibitor exposure was associated with adjusted hazard ratios of 1.99 for basal cell carcinoma, 1.69 for squamous cell carcinoma, and 1.54 for melanoma in a 56,209-patient retrospective cohort.

The ABCDE warning signs help spot melanoma early, so counsel your patients regarding Asymmetry, Border, Color, Diameter, and Evolving (the mole or spot changes in size, shape, or color. It may also start to bleed, itch, or crust).

PORT is recommended for patients with cSCC having close or positive margins that cannot be corrected with further surgery (secondary to morbidity or adverse cosmetic outcome). In patients with cSCC, PORT is recommended for T3 and T4 tumors—both strong recommendations with moderate to low evidence quality.

“These results would really shift our practice from starting it once patients have developed numerous skin cancers to starting it earlier. We still need to do a better job of identifying who will actually benefit, as roughly only half of patients will develop multiple skin cancers.” – Lee Wheless, MD, PhD

Basal cell carcinoma, while common, rarely leads to death when detected and treated early. Physicians should be aware of the seven warning signs that can be mistaken for harmless skin conditions.

The integration of AI in skin cancer diagnostics not only improves the accuracy of diagnoses—achieving a sensitivity of 81.1% and specificity of 86.1%—but also supports the broader application of AI tools in enhancing patient care across various medical specialties.