This article dives into information and the causes of five drug-induced diseases (DIDs) including hyponatremia/SIADH, pulmonary disease, GI bleeding, QT prolongation/Torsades de pointes, and hypoglycemia. Because research reviewed by the FDA for drug approval does not always include DIDs, it is the physician’s responsibility to monitor for DIDs and think twice about prescribing agents that could lead to DIDs.