
AHA published geriatric-focused revascularization guidelines recognizing older adults present atypically—with dyspnea, fatigue, confusion instead of chest pain—requiring early testing when nonspecific symptoms appear. Framework emphasizes patient-centered outcomes like days-alive-out-of-hospital over traditional metrics, advocating shared decision-making that addresses what matters most to older patients facing complex coronary disease.
🔬 CLINICAL CONSIDERATIONS
- Atypical presentation delays diagnosis: Older adults present with dyspnea, fatigue, syncope, confusion, or functional decline rather than chest pain, requiring lower threshold for objective cardiac testing
- Frailty predicts procedural risk: Multiple comorbidities and age-related body changes contribute to frailty, which independently predicts cardiovascular events and increased risk after invasive procedures
- Cognitive assessment enables consent: Pre-procedure cognitive evaluation necessary to obtain proper informed consent or identify need for family/proxy involvement in decision-making
- Pharmacotherapy requires adjustment: Age-related pharmacokinetic and pharmacodynamic changes demand careful medication selection and dosing for procedural anticoagulation and antiplatelet therapy
🎯 PRACTICE APPLICATIONS
- Implement early objective testing protocols for older patients with nonspecific symptoms and cardiovascular risk factors
- Assess functional status and frailty before procedures to predict recovery trajectory and inform risk discussions
- Document what-matters-most conversations exploring patient preferences for symptom relief versus life extension before revascularization
- Establish multidisciplinary team approach including geriatrics consultation for complex older patients considered for intervention
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