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JCI InsightHeterogeneity of B-cell Lymphopoiesis in Patients with Premalignant and Active Myeloma

By using mass cytometry (CyTOF) analysis, the researchers profiled plasma cells (PCs) and their B cell lymphopoiesis in BM samples from patients with monoclonal gammopathy of undetermined significance, smoldering multiple myeloma (MM), and active MM in order to better understand the heterogeneity of MM.