When atypical AMD is suspected, additional multimodal imaging and a more detailed medical history are required to establish the correct diagnosis. The medical history, clinical examination, and retinal imaging findings of a 69-year-old White man with a long-standing medical history of schizophrenia, bilateral visual decline, nyctalopia, and blurred vision were sufficient evidence for the doctors to establish a presumed diagnosis of thioridazine retinal toxicity. Although it is a rare diagnosis due to the introduction of newer medications, patients with an underlying psychiatric history and atypical retinal findings on examination may have been or are currently taking the culprit psychotropic medication.