MDLinxBipolar Disorder Linked to Early Death More than Smoking

Impact of Bipolar Disorder on Mortality: Unveiling the Extent of Risk and Comorbidity Connections

This comprehensive study reveals significant findings regarding the mortality risk associated with bipolar disorder, underscoring its seriousness compared to other health and lifestyle factors. Conducted by the University of Michigan and published in Psychiatry Research, the study compares the premature death risks in individuals with bipolar disorder against other known risk factors. It provides a stark view of the heightened mortality risks and the underlying health and lifestyle factors contributing to this increased risk, urging a reevaluation of prevention and intervention strategies.

Key Points:

1. Elevated Mortality Risk: Individuals with bipolar disorder were found to be 4-6 times more likely to die prematurely compared to those without the condition.
2. Comparison with Smoking: The risk of early death for people with bipolar disorder is significantly higher than for individuals who have ever smoked.
3. Broad Data Analysis: The study analyzed data from 1,128 participants in a long-term bipolar disorder study and more than 18,000 patients from Michigan Medicine’s primary care system.
4. Comorbidity with Hypertension: High blood pressure was noted as a significant factor, with those affected being five times more likely to die prematurely.
5. Prevalence of Smoking in Bipolar Disorder: A higher incidence of smoking was observed among individuals with bipolar disorder compared to those without.
6. Gender Differences: Females with bipolar disorder showed a slightly lower risk of early death.
7. Associated Health Conditions: Higher incidences of asthma, diabetes, migraines, fibromyalgia, and thyroid conditions were found in individuals with bipolar disorder.
8. Mental Health Medication: No direct association was found between mortality risk and the duration of mental health medication use.
9. Need for Early Intervention: The study emphasizes the importance of early intervention and more comprehensive health and lifestyle management for individuals with bipolar disorder.

“Bipolar disorder is never going to be listed on the death certificate as the main cause of death, but it can be an immediate or secondary contributor to a death, including in suicides.”
– Anastasia Yocum, PhD, lead author of the study and data manager of the research program at the Heinz C. Prechter Bipolar Research Program

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