
ACOG’s 2025 guideline establishes evidence-based recommendations for cervical ripening in term, singleton, vertex pregnancies with intact membranes. With 33.7% of US births involving induction and 84% of those patients requiring cervical ripening, this guideline directly shapes daily L&D nursing practice.
⚖️ Clinical Considerations
- Prostaglandins are contraindicated in patients with prior cesarean or uterine surgery; mechanical methods remain an option
- Combined balloon catheter plus 25 mcg misoprostol at 30 mL volume identified as safest, most effective strategy
- Outpatient ripening is conditionally recommended for low-risk patients using dinoprostone or balloon catheters
- Trauma-informed care requires assessing patient distress before choosing vaginal versus oral methods
🎯 Practice Applications
- Screen all induction patients for prior cesarean before initiating prostaglandin agents
- Document shared decision-making conversations including patient values and method preferences
- Apply trauma-informed assessment when selecting oral versus vaginal ripening method
- Educate patients that induction typically extends labor duration versus expectant management
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