Journal of Neurology, Neurosurgery & PsychiatryAutoimmune Encephalitis: Proposed Best Practice Recommendations for Diagnosis and Acute Management

When there was insufficient or conflicting evidence, core authors from the Autoimmune Encephalitis Alliance Clinicians Network assessed the literature and administered an electronic survey to each member to get their personal opinions. The poll received 68 responses from respondents in 17 different nations. For patients with a general presentation, 84% of responders chose corticosteroids alone or in combination with other treatments (intravenous IG or plasmapheresis), 74% for patients who presented with faciobrachial dystonic seizures, 63% for NMDAR-IgG encephalitis, and 48.5% for classical paraneoplastic encephalitis. A summary of the diagnostic and therapeutic recommendations is provided at the end of the manuscript, which also includes a detailed presentation of the survey data.