CBD Gummies: Metabolic Factors and Delayed Onset Challenge Therapeutic Efficacy
Cannabidiol (CBD) gummies present a unique challenge in cannabinoid therapeutics due to their delayed onset of action. This summary outlines key aspects of CBD gummy consumption, including absorption factors, duration of effects, and potential benefits. Understanding these elements is crucial for physicians advising patients on CBD use, particularly in comparison to other administration methods.
Key Points:
- Onset of action: Up to 2 hours, slower than other methods like vaping
- Duration of effects: Typically 4-6 hours
- CBD half-life: Up to 5 days after consumption
- Non-intoxicating: CBD does not produce a “high” like THC
Factors Affecting Absorption:
- Metabolism rate
- Body weight
- Individual biology
- Consumption with high-fat meals may enhance absorption
- Piperine (found in black pepper) may increase absorption rate
Dosage Considerations:
- Typical starting dose: 10-20 mg
- Recommendation: Start low, increase gradually
- High tolerance: Humans can tolerate up to 1,500 mg/day
Types of CBD Products:
- Full-spectrum: Contains all cannabinoids and terpenes
- Broad-spectrum: Contains many cannabinoids, excluding THC
- CBD isolate: Pure CBD only
Additional Points:
- “Entourage effect”: Full-spectrum and broad-spectrum may be more effective
- Quality control: Importance of reputable sources due to mislabeling issues
- Individual response: Effects may vary between patients
HCN Healer Handbook
“CBD gummies are like time-release vitamins. They take longer to work – up to 2 hours – but the effects can last 4-6 hours. This slower start is because the body needs to digest them first. We’ll start with a small amount, about 10-20 mg, and adjust if needed. Everybody responds differently. Factors like their size, metabolism, and even what they’ve eaten can affect how quickly it works. It’s crucial to get CBD from trusted sources – quality varies widely. Also, always let me know about any other medications you or your loved one is taking. We’ll watch closely to see how you respond and make changes if necessary to find what works best.”
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