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Annals of Internal MedicineHydroxychloroquine in Nonhospitalized Adults With Early COVID-19

No effective oral therapy exists for the outpatient treatment of COVID-19. Hydroxychloroquine has in vitro activity against SARS-CoV-2 and has been proposed as a potentially effective treatment. This randomized double-blind, placebo-controlled trial investigated whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients.

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