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ACP InternistMKSAP Quiz: 12-week History of Night Sweats, Fevers, Weight Loss

This 33-year-old man reports no other symptoms, and he isn’t on any medication. Medical history is unremarkable. CBC and comprehensive profile are normal, as are serum alpha-fetoprotein and beta-HCG. CT scans reveal bulky diffuse adenopathy. A cervical node biopsy showed poorly differentiated carcinoma. What is the appropriate therapy?

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