Pharmacogenomics (PGx) researches how germline (or inherited) alterations impact a person’s receptivity to medication. Almost everyone has a clinically significant variant of one or more pharmacogenes. Genetic variations in PK, PD, and HLA are linked to variations in drug response. Evidence only supports the utility of PGx testing for the four genes CYP2C19, CYP2D6, HLA-B15:02, and HLA-A31:01 in mental health. Fill out the CPE exam and submit it online at www.pharmacist.com/education if you’re interested in receiving 1 hour of CPE credit for this activity.