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JCI Insight is an Gold Open Access journal that has a 2021 Impact Factor of 9.484. The Journal publishes well-executed, high-quality studies that provide meaningful contributions to the understanding of the biology and/or treatment of disease, with an emphasis on clinically relevant basic and translational research. Submissions are welcome from all biomedical specialties, including autoimmunitygastroenterologyimmunologymetabolismnephrologyneuroscienceoncologypulmonology, vascular biology, and many others.

JCI Insight is self-published by the American Society for Clinical Investigation (ASCI), a nonprofit honor organization of physician-scientists established in 1908. JCI Insight serves to fulfill the ASCI’s objective to advance medical science through the publication of clinically relevant research reports.