HCN Essentials: Hereditary Angioedema Challenges | Switching Antifibrotics in IPF | CrCl CalculatorAugust 17, 2021 | Trending in Healthcare Dermatology Hereditary Angioedema is Often Misdiagnosed Often undiagnosed due to its unspecific symptoms, hereditary angioedema (HAE) is a tricky condition that causes many patients unnecessary suffering with unnecessary surgeries and invasive diagnostic/therapeutic interventions. Read on to educate yourself on some of the alarming numbers on the orphan disease. Read full article Allergy & Immunology Switching Antifibrotic Agents in Idiopathic Pulmonary Fibrosis (IPF) Source: BMC Pulmonary MedicineFindings: IPF patients who switched from one antifibrotic therapy to the alternative — whether from pirfenidone (Esbriet) to nintedanib (Ofev, Vargatef) or the other way around – had improved survival. This observation held true whether the reason for switch was disease progress or tolerance issues.Design: Multi-center retrospective cohort study; 262 patients Read full article Cardiology Creatinine Clearance Calculator MDCalc.com offers this helpful tool, which calculates creatinine clearance (CrCl) according to the Cockcroft-Gault equation. The tool also allows height input, which analyzes BMI and provides a modified estimate and range. Read full article