HCN Essentials: Osteoporosis Management Controversies | Lipid-Lowering Therapy Changes | Vax: Immunity “Waning”? | COVID: One Year LaterOctober 05, 2021 | Trending in Healthcare Cardiology Profound Changes in Lipid-Lowering Therapy Coming with New Agents Targeting LP(a) and Triglycerides Our understanding of lipid pathology is shifting from what might be called the “LDL hypothesis” to the “atherogenic lipoprotein hypothesis.” LDL is just a surrogate of the actual process of lipoprotein interaction with the arterial wall. This shift in understanding is driving a host of budding therapies with novel approaches to targeting key atherogenesis players like lipoprotein(a) and triglycerides. Read full article Allergy & Immunology COVID-19 Vaccination: Evidence of Waning Immunity is Overstated Evidence is mounting that much of the concern about waning immunity to COVID-19 is overstated and that vaccines provide high levels of protection against the respiratory disease and its variants over the long-term. Immunologically, plasmablast and B-cell response after mRNA vaccination is long-lived and memory B cells increase over at least six months. And in the field, the evidence is that vaccination is doing what it is intended to do: reduce the severity and spread of the infection. Read full article Allergy & Immunology Symptoms and Health Outcomes Among Survivors of COVID-19 Infection After One Year Curious about the long-term impacts of COVID-19? A new study that involved 2,433 hospitalized patients found that the most common symptoms after one year were fatigue, sweating, chest tightness, anxiety, and myalgia. The study, conducted in Wuhan, China, one of the global epicenters of the pandemic, also found that patients with severe disease had more serious long-term issues, including a high incidence of COPD. Read full article
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