HCN Oncology Year-in-Review: Lung CancerDecember 21, 2021 | Oncology Internal Medicine Non-Small Cell Lung Cancer Treatment Regimens Bookmark this page – or download the information directly, if you prefer – to ensure you’re always connected to the latest and greatest information on the very best in NSCLC treatment regimens (NCCN Guidelines). Read full article Endocrinology, Diabetes, Metabolism Does Metformin Improve Outcomes in Nondiabetic, Unresectable Stage III NSCLC Treated with Chemoradiation? Publication: JAMA Oncology Objective: With NSCLC having relatively poor outcomes and the significant data supporting the use of metformin as an antineoplastic agent, the researchers wanted to compare overall or progression-free survival in chemoradiation alone vs. chemoradiation + metformin stage III NSCLC patients. Design: Randomized clinical trial, open-label, phase 2 study; 167 eligible patients Read full article Hematology/Oncology Sintilimab Plus Chemo Prolongs Survival in Advanced Non-Small Cell Lung Cancer The encouraging results of the phase 3 ORIENT-11 trial, which included 397 patients with previously untreated, locally advanced metastatic non-squamous NSCLC without sensitizing EGFR or ALK aberrations, were published in the Journal of Thoracic Oncology.