Long-Term Survival in BC | Managing CRC in Younger Patients | Consortium Report: RhabdomyosarcomaJuly 06, 2021 | Oncology Internal Medicine Assessment of 25-Year Survival of Women with ER+/ERBB2- Breast Cancer Treated w. and without Tamoxifen Therapy This Original Investigation from JAMA Network Open assesses whether clinically used markers of breast cancer, such as tumor size, tumor grade, progesterone receptor status, and Ki-67 status, are associated with long-term (25-year) survival as they are with short-term survival. The study was a secondary analysis of data from a subset of 565 women who participated in the Stockholm tamoxifen (STO-3) trial from 1976 to 1990. Read full article Gastroenterology Considerations in the Management of Younger Patients With Colorectal Cancer It is important for young people, caregivers, and healthcare providers to recognize possible symptoms of colorectal cancer (CRC) and arrange a colonoscopy or other tests when necessary. This article presents a thorough review of CRC and its impact on young patients, including a hypothesis for the increase of cases, screening recommendations, demographic features, symptoms, and recommendations for physicians. Read full article Internal Medicine Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report from an International Consortium Despite aggressive therapy, the 5-year survival rate for patients with metastatic or recurrent rhabdomyosarcoma – the most common soft tissue sarcoma of childhood – remains poor, and beyond PAX-FOX01 fusion status, no genomic markers are available for risk stratification. This international consortium study was designed to determine the incidence of driver mutations and their association with clinical outcome. Read full article
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