R2CHOP | 5 Anticancer Foods | New Trodelvy ApprovalApril 20, 2021 | Oncology Hematology Addition of Lenalidomide to R-CHOP Improves Outcomes in Newly Diagnosed Diffuse Large B-Cell Lymphoma in a Randomized Phase II US Intergroup Study ECOG-ACRIN E1412 The ECOG-ACRIN E1412 study demonstrated a potential clinical benefit of adding lenalidomide to R-CHOP (rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone) (R2CHOP) in newly diagnosed patients regardless of cell-of-origin (COO) and in patients with activated b-cell-like (ABC) diffuse large B-cell lymphoma (DLBCL). Although the results are not practice changing, they support further studies of lenalidomide and/or novel lenalidomide analogues in frontline therapy of DLBCL. Read full article Dermatology 5 Cancer-Fighting Foods That Have Researchers’ Attention According to the American Institute for Cancer Research, a diet filled with a variety of vegetables, fruits, whole grains, beans, and other plant foods helps lower risk for many cancers, thanks to their bioactive compounds. Things like bergamottin. Isothiocyanates. Polyphenols. Continue reading to discover five foods that have the potential to fight cancer, including pancreatic, skin, and more. Read full article Internal Medicine FDA Approves Sacituzumab Govitecan for Advanced Urothelial Cancer This new indication marks the second FDA approval for sacituzumab govitecan (Trodelvy, Immunomedics) and was based on the phase 2, single-arm TROPHY-U-01 main efficacy endpoints in objective response rate (ORR) and duration of response (DOR). With a relative 5-year survival rate of 5.5%, this is a significant advancement for patients with metastatic urothelial cancer (mUC), the most common type of bladder cancer. Read full article