According to the researchers who published their findings in JAMA Network Open, the percentage of chronic pain patients using non-drug therapies without opioids remained relatively stable at 20% from 2011 to 2016, but it then increased quickly, reaching 40% in 2019. Non-opioid therapy is preferred for treating chronic pain, according to CDC guidance. However, neither the use of opioids alone nor in combination with non-drug treatments for chronic pain significantly decreased following the 2016 guidance. In fact, while about 3% to 15% of patients used opioids alone, their use increased slightly between 2016 and 2018 (from about 10% to 15% of patients).