A Bleeding Diathesis in a 65-Year-Old Woman with Newly Diagnosed Breast Cancer

After diagnosis during a partial mastectomy, this patient’s estimated blood loss was 58 mL, causing anemia and requiring a red blood cell transfusion along with ventriculoperitoneal drain placement. With a substantive bleeding history before the diagnosis, what would you do next with this patient?

Work her up for von Willebrand disease?

Do a complete blood count test to look at platelet count, a peripheral smear to look at the morphology of the platelets, and a coagulation profile?

Offer genetic testing for fibrinogen disorders?

What would your next steps be? Read the full case presentation and expert opinion to see how your peers responded.