DIET & NUTRITION 
PATIENT EDUCATION 
OBESITY/WEIGHT MANAGEMENT 
EXERCISE/TRAINING 
LEGAL MATTERS 
GUIDELINES/RECOMMENDATIONS In a prospective study following the diet and activity records of more than 100,000 individuals in France, artificial sweeteners were positively correlated with cardiovascular diseases. Analyzing 900,000 person-years of data showed:
- Total artificial sweetener intake was associated with CVD risk
- Artificial sweeteners were more strongly associated with cerebrovascular disease
- Aspartame was associated with increase cerebrovascular events
- Acesulfame K and sucralose were associated with increased coronary heart disease risk