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The New England Journal of MedicineBuprenorphine vs. Methadone for Opioid Use Disorder in Pregnancy

In this cohort study of insurance data over an 18-year period covering more than 15,000 pregnancies that involved methadone or buprenoprine use, buprenorphine in pregnancy was associated with a lower risk of adverse neonatal outcomes versus methadone use. However, the risk of adverse maternal outcomes was similar.

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