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Annals of Internal MedicineEstimated Effect of Parathyroidectomy on Long-Term Kidney Function in Adults with Primary Hyperparathyroidism

In this target trial emulation involving nearly 44,000 patients with primary hyperparathyroidism (PHPT), similar declines in kidney function at 5 and 10 years were seen in patients managed with parathyroidectomy and in those managed nonoperatively. Thus, in this study, parathyroidectomy had no effect on long-term kidney function in older adults with PHPT.