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The Ocular SurfaceEvaluation of Ocular Neuropathic Pain

Evaluating the Effectiveness of Ocular Neuropathic Pain Questionnaires


The recent study aimed to assess the quality and effectiveness of various questionnaires used to evaluate ocular neuropathic pain. The research focused on the psychometric properties, validity, and reliability of these questionnaires.

Study Design

  • A comprehensive literature search was performed on MEDLINE, PubMed, EMBASE, PsycINFO, and The Cochrane Library.
  • Articles evaluating questionnaires for ocular neuropathic pain and its associated aetiologies were included.
  • Data on psychometric properties, validity, and reliability of the questionnaires was extracted and analysed using a set of quality criteria.

According to the American Academy of Ophthalmology, nearly one in three people experience chronic eye discomfort.

Key Findings

  • The search generated 1,738 results with 61 publications meeting the inclusion criteria.
  • These publications covered 28 questionnaires including 3 ocular pain, 12 dry eye disease, 2 blepharitis, 2 refractive surgeries, 3 contact lens wear, 3 Sjogren’s Syndrome, and 3 that were non-disease specific.
  • The Contact Lens Discomfort Index (CLDI) had the highest rated psychometric properties.
  • The English version of the Ocular Comfort Index (OCI) provided the most data on psychometric properties (9 out of 10 criteria).
  • Most ocular pain and disease-specific questionnaires contained appropriate items to assess ocular pain in specific populations.
  • Non-disease-specific ophthalmic questionnaires demonstrated poor reliability and validity when evaluating ocular pain.

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