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The New England Journal of Medicine
Among more than 200 adolescents 12 to 18 years of age over a 68-week period, nearly 75% of those in the treatment group experienced weight loss of > 5%, compared with only about 15% of those with placebo plus lifestyle intervention. GI adverse events were more common in the treatment group.
Endocrinology, Diabetes, Metabolism November 14th 2022
MedPage Today
To combat weight gain after bariatric surgery, a single weekly 1-mg dose of semaglutide outperformed liraglutide at 3-mg daily. About half the semaglutide group were able to lose more than 10% of their body weight, versus about 1/3 for the liraglutide group.
Cleveland Clinic Journal of Medicine
Hyperglycemia is associated with poor clinical outcomes in critically ill patients. Most medical societies recommend less stringent glucose control, in the range of 140 to 180 mg/dL, for critically ill patients. In this population, although glucose management is essential, hypoglycemia is associated with increased mortality. Enhancing the amount of time glucose levels are in the target range and minimizing glycemic variability have been associated with improved outcomes in critically ill patients.
Endocrinology, Diabetes, Metabolism April 27th 2022