Articles related to SKIN CONDITIONS/RASH

A 77-year-old man with a history of solar keratoses presents a progressively enlarging and darkening lesion on his right cheek, as observed by his wife over a year, with a dermoscopic examination revealing asymmetric pigmented follicular openings and greyish globules and dots.

On July 11, 2023, participate in the AMCP PIE Webinar to learn more about the potential of VP-102, an investigational medication for molluscum contagiosum that is now undergoing FDA assessment.

Grappling with the diagnostic challenges of Prurigo nodularis requires not only a comprehensive patient evaluation but also a deeper understanding of the disease’s complex pathophysiology and associated comorbidities. Clinicians can leverage this knowledge to devise effective, individualized treatment strategies.

A 37-year-old man presented with persistent swelling, limited range of motion, and loss of hand dexterity in both hands. He had a history of IV drug use, including opiates and methamphetamine. The examination showed diffuse swelling without joint inflammation. Lab tests were normal, and imaging revealed soft-tissue swelling. The diagnosis was puffy hand syndrome, a common complication of IV drug use. Treatment options are mainly symptomatic, including discontinuation of IV drug use and the use of low-stretch bandages and compression gloves. Puffy hand syndrome, often unrecognized by general practitioners, should be considered in patients with swelling and limited hand function who have a history of IV drug use. The syndrome involves progressive fibrosis of subcutaneous tissues due to repeated injection-induced vascular and dermal sclerosis. Diagnosis is based on clinical presentation, history, and evaluation ruling out other conditions. Treatment focuses on symptomatic relief and cessation of IV drug use.

A 75-year-old man visited the dermatology clinic with concerns about multiple actinic keratoses and a black discoloration on his right hand and fingers. It is noteworthy that over the past 12 to 14 years, during his retirement, the patient has experienced black discoloration on his right hand after peeling apples for pies multiple times each year. This discoloration occurs on the hand that holds his carbon knife and stainless steel peeler and typically disappears within a few days. Upon examination, the right palm exhibited black macular discoloration along the skin lines, particularly prominent on the palmar aspect of the fingers. The patient’s hands also displayed dryness and roughness upon palpation. Can you identify the diagnosis?

Approved for AD in adults a year ago, abrocitinib is now available for individuals over 12 years old with moderate to severe atopic dermatitis that is not adequately controlled with other systemic therapy.