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Recent research published in the Journal of the Endocrine Society demonstrates that vitamin D supplementation combined with calcium may effectively lower blood pressure in older adults with obesity. The year-long study of 221 participants aged 65 and older examined two dosage levels – 600 IU/day and 3,750 IU/day – with both groups receiving 250 mg of calcium citrate. The findings reveal significant blood pressure reductions regardless of dosage, with particular benefits observed in participants who had obesity and low initial vitamin D levels.
Key Points:
- Study participants experienced average decreases of 3.5 mm Hg in systolic blood pressure and 2.8 mm Hg in diastolic blood pressure, independent of vitamin D dosage
- Both 600 IU/day and 3,750 IU/day vitamin D doses, combined with 250 mg calcium citrate, showed comparable effectiveness
- Participants had initial serum 25-hydroxy vitamin D levels between 10-30 ng/mL, classified as insufficient to deficient
- Vitamin D’s blood pressure-lowering mechanisms include calcium regulation, anti-inflammatory effects, and modulation of the renin-angiotensin-aldosterone system
- Clinical implementation requires pre-supplementation vitamin D testing and should be integrated into a comprehensive treatment approach including diet, exercise, and weight management
“A simple blood test can reveal any deficiency that may be contributing to blood pressure issues. If levels are low, supplements or a bit of natural sunlight exposure (when safe) can help improve vitamin D status over time.”
– Dr. Rita Hawle, Clinical Dietitian and Nutritionist
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