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HealthlineEverything You Should Know About Magnesium Glycinate


Magnesium glycinate, a highly bioavailable form of magnesium, has gained attention for its potential health benefits and role in addressing magnesium deficiency. This article examines the uses, benefits, and considerations of magnesium glycinate supplementation, providing clinicians with essential information to guide patient care and recommendations.

Key Points:

  • Magnesium glycinate is formed by combining elemental magnesium with the amino acid glycine, resulting in high bioavailability and absorption through the small intestine.
  • The Recommended Dietary Allowance (RDA) for magnesium ranges from 310-420 mg/day for most adults, depending on age and sex.
  • Potential benefits of magnesium supplementation include lowering blood pressure, reducing the risk of stroke and cardiovascular disease, improving bone health, and preventing migraine headaches.
  • Approximately 50% of people in the United States may have a magnesium deficiency, with common causes including alcohol use, chronic diarrhea, poorly managed diabetes, malabsorption disorders, and certain medications.
  • Magnesium glycinate supplements are available in pill or powder form and should be taken with food to reduce stomach upset. Dosage and potential interactions with medications should be discussed with a healthcare professional.
  • Natural sources of magnesium include dark green leafy vegetables, nuts, seeds, whole grains, and fish. Organic soils may provide produce with higher magnesium content.

Chronic inadequate magnesium intake, particularly frequent in old age, has been associated with an increased risk of multiple clinical conditions including hypertension and stroke. (Nutrients)


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