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The New England Journal of MedicineBurnout, Depression, and Diminished Well-Being among Physicians


Recent research reveals significant challenges in physician well-being, with a critical examination of burnout and depression as key measuring constructs. Although burnout affects approximately 38-50% of US physicians (depending on measurement criteria), the lack of standardized definition presents challenges in assessment and intervention. The article examines system-level and individual interventions, highlighting the critical role of workload reduction and institutional support in improving physician well-being.

Key Points:

  • Workload emerges as the primary driver of diminished physician well-being, with studies showing a direct correlation between increased work hours and depression rates. Residents working 90+ hours showed nearly triple the increase in depressive symptoms compared to those working 40-45 hours.
  • System-level interventions demonstrate superior effectiveness compared to individual interventions. The addition of scribes, clerical support, and task redistribution to non-physician team members significantly improves physician satisfaction and reduces burnout.
  • Women physicians face disproportionate challenges, with higher rates of depression, burnout, and suicidality compared to male colleagues. Up to 50% of female faculty report harassment, and 75% consider reducing hours within 6 years post-training due to work-family conflicts.
  • Depression rates increase 5-6 times during residency compared to pre-residency levels, with 25-30% of physicians screening positive for depression during training.
  • Evidence supports mindfulness-based interventions, cognitive behavioral therapy, and exercise as effective individual-level interventions, though their impact is smaller than system-level changes.

HCN Medical Memo
The evidence clearly points to workload reduction as the primary lever for improving physician well-being. Although individual interventions like mindfulness training have value, institutional commitment to systemic changes, particularly in workflow and support staff allocation, offers the most significant impact on physician wellness.


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